PLENARY LECTURES
Saturday, July 3, 2010
18:00 - 19:00
L01 - Roger Y. Tsien (La Jolla, USA)
Probing neurons and brains with molecules and photons
This lecture will deal about extending genetically encoded probes to longer wavelengths, electron microscopic resolution, or the assessment of new protein synthesis and turnover. Also, synthetic molecules may help clinicians visualize peripheral nerves during surgery and protease activities in brains that have undergone strokes.
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Sunday, July 4, 2010
08:30 - 09:30
L02 - Oscar Marin (Alicante, Spain)
Cortical interneuron development in health and disease
Gamma-aminobutyric acid-containing (GABAergic) interneurons play major roles in the function of the cerebral cortex. In addition, growing evidence suggest that disruption of interneuron function is common to several psychiatric disorders, such as schizophrenia. Given their extraordinary diversity, understanding cortical interneuron development seems crucial to shed light into their function in cortical processing, both in health and disease.
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Sunday, July 4, 2010
17:30 - 18:30
L03 - Michael Tomasello (Leipzig, Germany)
The human adaptation for culture
Human beings are biologically adapted for cultural life in ways that other primates are not. Humans have unique motivations and cognitive skills for understanding other persons as cooperative agents with whom one can share emotions, experience, and collaborative actions (shared intentionality). The motivations and skills involved emerge in human ontogeny at around one year of age, as infants begin to participate with other persons in various kinds of collaborative and joint attentional activities (cultural practices), including linguistic communication. Chimpanzees understand important aspects of intentional action - specifically that others pursue goals and perceive things relevant to those goals - especially in competitive situations. But our nearest primate relatives do not seem to have the motivations and cognitive skills necessary to engage in activities involving collaboration, shared intentionality, and, in general, things cultural.
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Monday, July 5, 2010
08:30 - 09:30
L04 - Stanislas Dehaene (Gif Sur Yvette, France)
Understanding the consciousness code in the human brain
Identifying the brain mechanisms of conscious-level processing is a major
challenge for cognitive neuroscience. Time-revolved neuroimaging methods
such as EEG, MEG, and intracranial recordings, during conscious perceptual
processing, has revealed a global-workspace mode of cortico-thalamic
operation, with characteristic electrophysiological signatures that can be
of help to detect conscious states in patients with impaired communication.
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Monday, July 5, 2010
17:30 - 18:30
Presidential lecture
L05 - Melitta Schachner (Hamburg, Germany)
Recognition molecules in synaptic plasticity and regeneration
Neural cell adhesion molecules were discovered as important determinants in ontogenetic development. Initially unexpected, yet particularly exciting are their functions in the adult nervous system when they recapitulate, at least to some extent, their developmental features in synaptic plasticity, in regeneration after trauma and in prevention of neurodegenerative diseases: that is when the nervous system remains or is required to be "on the move".
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Tuesday, July 6, 2010
08:30 - 09:30
L06 - May-Britt Moser (Trondheim, Norway)
The brain's mechanisms for mapping and remembering space
Cognition is thought to reflect computations in widespread and entangled neural circuits but the nature of these computations is poorly understood. In this lecture I will show how a representation of an animal’s current and past location is created in grid cells and other dedicated cell types in networks of the entorhinal cortex and the hippocampus, many synapses away from the sensory cortices.
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Tuesday, July 6, 2010
17:30 - 18:30
L07 - Tobias Bonhoeffer (Munich, Germany)
How activity changes synapses in the mammalian brain
Support contributed by the Kavli Foundation
One of the most fundamental properties of the brain is its ability to adapt rapidly to environmental changes. This is mainly achieved by changes in synaptic connectivity. Research in recent years has provided important new insights into the rules and mechanisms underlying synaptic plasticity. At the same time, novel imaging techniques have made it possible to investigate morphological as well as functional plasticity at the level of individual neurons in the intact brain. The lecture will discuss how these approaches are beginning to close the gap between traditional cellular and systems studies, and how they will enable us to obtain a much more complete understanding of the phenomenon of synaptic plasticity and its role for cortical function.
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Wednesday, July 7, 2010
08:30 - 09:30
L08 - Maria Spillantini (Cambridge, United Kingdom)
What can protein aggregates tell us about neurodegenerative diseases?
Several neurodegenerative diseases of the brain are characterized by the presence of intracellular protein aggregates. These aggregates can contain alpha-synuclein as in Parkinson's diseases Lewy bodies or the microtubule associated protein tau as the neurofibrillary tangles in Alzheimer's diseases and other tauopathies.
The relevance of protein aggregates for neurodegeneration has been determined by the identification of genetic mutations in genes encoding for the aggregated proteins. However, the specific role of the aggregates and the structure of the toxic species is still debated. Transgenic animal models can help us to understand the pathological mechanism and provide important tools for identifying and testing new therapies.
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Wednesday, July 7, 2010
13:05 - 14:05
L09 - Arturo Alvarez-Buylla (San Francisco, USA)
Regional specification of postnatal neural stem cells
The largest germinal region in the adult mammalian brain occurs in the subventricular zone (SVZ) in the walls of the lateral ventricles. Recent work from the laboratory has shown that neural stem cells retain an epithelial apical-basal organization and are surrounded by ependymal cells in striking pinwheel architecture. Other recent work from our laboratory has demonstrated that the stem cells of the SVZ are not homogeneous. Instead, stem cells located in different subregions of the SVZ generate distinct types of neuronal progeny that migrate to the olfactory bulb. In vitro studies suggest that the adult SVZ is a mosaic of multipotent progenitors capable of generating both neurons and glial cells. However, neurons generated at specific locations appear to be prespecified. I will discuss these findings and more recent work on the signals that may be associated with the proliferation and specification of SVZ subregions.
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SPECIAL LECTURES
Sunday, July 4, 2010
13:00 - 14:30
Fondation IPSEN awarding lectures
SL01 - To be announced
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Sunday, July 4, 2010
13:00 - 13:45
EBBS / Behavioural Brain Research Prize lecture
SL02 - John Aggleton (Cardiff, United Kingdom)
Bridging the gap between temporal lobe and diencephalic memory systems
While the importance of the hippocampus for our day-to-day memory remains undisputed, there is great uncertainty about how other brain regions work in concert with the hippocampus to support memory. The talk examines the direct and indirect links between the hippocampus and the medial diencephalon using a mixture of neuroanatomical, clinical, and behavioural evidence. Convergent, new evidence indicates that temporal lobe amnesia and diencephalic amnesia reflect dysfunctions in the same system, and that to understand the hippocampus it will be necessary to understand the roles of its connections with the anterior thalamic nuclei and retrosplenial cortex.
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Sunday, July 4, 2010
13:00 - 13:45
Gertrud Reemtsma Foundation – K.J. Zuelch lecture
SL03 - David N. Louis (Boston, USA)
Malignant gliomas: Small steps and giant leaps
Malignant gliomas are the most common and the most difficult to treat of brain tumors. However, work over the past two decades has shed light on the biological basis of malignant gliomas. Like other cancers, malignant gliomas arise when genetic alterations deregulate critical growth regulatory pathways, probably via a stage of glioma stem cells. This biological information has now begun to affect diagnosis and treatment of patients with malignant gliomas, including through targeted therapies.
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Monday, July 5, 2010
13:00 - 13:45
Dargut and Milena Kemali Foundation lecture
SL04 - Jonas Frisén (Stockholm, Sweden)
New neurons in old brains
The brain has traditionally been viewed as a static organ, with little possibility for renewal. However, research the last years has demonstrated that new neurons derived from endogenous stem or progenitor cells are continuously added to discrete regions of the adult brain. The realization of the potential to generate new neurons has raised hope for new regenerative treatment paradigms for neurological and psychiatric diseases.
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Monday, July 5, 2010
13:00 - 13:45
FENS invited lecture
SL05 - Tadashi Isa (Okazaki, Japan)
Extrageniculate visual system in the control of visually guided saccades
The extrastriate visual pathway, mediated via the midbrain superior colliculus, is supposed to process salient visual stimuli to evoke saccades. I will first talk on how the salient stimuli are detected by the collicular local circuits based on our studies using slice preparations. Then I will discuss on the capacity of the extrageniculate pathway, referring to our behavioral and electrophysiological observations in monkeys with lesion to the primary visual cortex, an animal model of "blindsight".
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Monday, July 5, 2010
13:00 - 13:45
ERA-NET Neuron excellent paper in neuroscience Award
SL06 - Heidi O. Nousiainen (Helsinki, Finland)
Mutations in mRNA export mediator GLE1 result in a fetal motoneuron disease
The second non-lecturing Award winner is Asya Rolls, Rohovot, Israel with her publication "Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation"
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Tuesday, July 6, 2010
13:00 - 13:45
Hertie Foundation lecture
SL07 - Linda B. Buck (Seattle, USA)
Mechanisms of odor and pheromone sensing in mammals
Humans and other mammals can discriminate a vast array of chemicals in the external world. While most are sensed as odors, others act as pheromones and induce hormonal changes or instinctive behaviors. The identification of receptors for odorants and pheromones has provided molecular tools with which to explore how these chemicals are first detected and then translated by the brain into diverse perceptions and behaviours.
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Tuesday, July 6, 2010
13:00 - 13:45
Boehringer Ingelheim FENS Research Award
SL08 - Fekrije Selimi (Paris, France)
Unraveling synapse specificity using genetically modified mice
The formation of specific connections between different neuronal populations underlies the development of a functional mammalian brain. This highly sophisticated connectivity might rely on a combinatorial "molecular code" that defines each type of synapse. I will talk about a new strategy, the "synaptic protein profiling" approach, which allows the identification of the proteins present at a specific synapse type in a given neuronal population in vivo. This approach has enabled the identification of new signaling pathways tethered at a particular synapse, the parallel fiber/Purkinje cell synapse of the cerebellum, and can now be extended to the study of other synapses in the mouse brain.
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Tuesday, July 6, 2010
13:00 - 13:45
EDAB - Max Cowan lecture
SL09 - Colin Blakemore (Oxford, United Kingdom)
Death and transfiguration in the development and function of the brain
Max Cowan's discovery of neuronal death and selective elimination of connections during the development of the nervous system was counter-intuitive but seminal in its influence. "Regressive" events, regulated by complex interactions within the developing brain, are now seen to be crucial for the creation of exquisite organization on the basis of sparse genetic instruction. The concepts of adaptability and plasticity now dominate our view of the brain – not only during its development but also as part of its mature function and its response to damage and disease.
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Wednesday, July 7, 2010
12:00 - 13:00
FENS EJN Awards
FENS EJN Award 2010
SL10.1 - Wolfram Schultz (Cambridge, United Kingdom)
Subjective reward and risk coding
The lecture will describe how neural signals in human and primate brains code reward and risk signals in a subjective rather than objective manner. I will present data on temporal discounting, risk coding and the influence of risk on neural value signals. These results suggest good correlations between neuronal and behavioural processes and are compatible with the general notion that neural processing adapts to available environmental resources.
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FENS EJN Young Investigator Award 2010
SL10.2 - Pierre Paoletti (Paris, France)
Control of NMDA receptor activity: from molecular mechanisms to synaptic modulation
NMDA receptors are glutamate-gated ion channels that play key roles in numerous physiological and pathological processes of the CNS including synaptic plasticity, excitotoxicity, pain and schizophrenia. During the last decade, molecular studies on recombinant receptors have led to significant advances in our understanding of the molecular mechanisms that govern subunit-specific NMDA receptor activation and modulation. These results provide unique opportunities to develop new tools to manipulate specific NMDA receptor functions in their native synaptic environment.
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SPECIAL EVENTS
Saturday, July 3, 2010
15:45 - 17:15
SE01 - EJN Special Feature: The ever-changing brain
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Sunday, July 4, 2010
12:30 - 14:00
SE02 - EC symposium: "FP7: EU-driven funding opportunities in brain research"
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Sunday, July 4, 2010
18:45 - 20:15
SE03 - ECNP symposium: "Is depression a neurodegenerative disorder?"
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Sunday, July 4, 2010
18:45 - 20:15
SE04 - EDAB/Neuroethics Society/International Neuroethics Network symposium: "Global challenges in neuroethics"
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Sunday, July 4, 2010
18:45 - 20:15
SE05 - NENS symposium
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Monday, July 5, 2010
18:45 - 20:45
SE06 - COST ACTION symposium: "Histaminergic system and pain - therapeutic opportunities for H3 and H4 receptor antagonists"
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Tuesday, July 6, 2010
13:00 - 14:00
SE07 - New European Directive on animal research: Impact on European neuroscience
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Tuesday, July 6, 2010
18:45 - 20:15
SE08 - FENS/IBRO Alumni symposium: "Encoding dynamic information in neuronal circuits"
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Wednesday, July 7, 2010
12:00 - 13:00
SE09 - Breaking News in Neuroscience
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SYMPOSIA
Click on the number on the left to have the full description of the symposium.
| Sunday, July 4, 2010 |
| 09:45 - 11:15 |
| S01 | - | Alzheimer’s disease – Translation of molecular mechanisms into diagnostic and therapeutic approaches (chaired by: C. Haass, Munich) |
| S02 | - | Shaping functional architecture by oscillatory alpha activity (chaired by: O. Jensen, Nijmegen; B. Händel, Nijmegen) |
| S03 | - | Endocannabinoids in the synapse: Molecular diversity and division of labor (chaired by: I. Katona, Budapest) |
| S04 | - | Neurobiology of motor learning (chaired by: J.C. Rothwell, London; J.B. Nielsen, Copenhagen) |
| S05 | - | The making of neuronal circuits: Mechanisms promoting and preventing synapse formation (chaired by: C. Lohmann, Amsterdam; K. Gottmann, Düsseldorf) |
| S06 | - | Brain tumors: recent insights from stem cell research (chaired by: N.E. Savaskan, Zurich; M. Synowitz, Berlin) |
| S07 | - | The neurobiology of syntax (chaired by: K.M. Petersson, Nijmegen) |
| S08 | - | Mechanisms of memory storage in neocortex (chaired by: G.T. Finnerty, London) |
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Sunday, July 4, 2010 |
| 15:45 - 17:15 |
| S09 | - | Tracking the fate of memories: Networks of memory consolidation and reconsolidation in the brain (chaired by: F.P. Battaglia, Amsterdam; S.I. Wiener, Paris) |
| S10 | - | Interplay between Rabs and SNAREs in neuronal vesicular trafficking (chaired by: T. Galli, Paris) |
| S11 | - | Targeting protein-protein interactions in neurological disorder therapy (chaired by: P. Marin, Montpellier; J. Bockaert, Montpellier) |
| S12 | - | Impairment and repair of motor networks after spinal cord injury (chaired by: T.G. Deliagina, Stockholm) |
| S13 | - | The microcircuitry of selective attention: Physiology, pharmacology and modelling (chaired by: L. Chelazzi, Verona) |
| S14 | - | Development of neural maps – from specification to function (chaired by: W.A. Harris, Cambridge) |
| S15 | - | Emerging mechanisms in neurodegenerative disorders - The role of spreading depression (SD) (chaired by: M. Lauritzen, Copenhagen; F. Bari, Szeged) |
| S16 | - | The temporo-ammonic pathway: What does it do and why is it important? (chaired by: S. Thompson, Baltimore) |
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Monday, July 5, 2010 |
| 09:45 - 11:15 |
| S17 | - | Molecular mechanisms controlling stem and progenitor cells in CNS development (chaired by: S. Atanasoski, Basel) |
| S18 | - | New developments in brain protection and repair after cerebral ischemia ? (chaired by: D. Vivien, Caen) |
| S19 | - | The bad cop and the good cop: Regulation of neuronal function by the immune system (chaired by: S.A. Wolf, Zürich) |
| S20 | - | Biomarkers in attention-deficit/hyperactivity disorder: inattentive and combined types (chaired by: R.D. Oades, Essen) |
| S21 | - | Large scale interactions in brain networks and new ways to study them (chaired by: P. Fries, Nijmegen) |
| S22 | - | Visualizing hearing (chaired by: J.G.G. Borst, Rotterdam) |
| S23 | - | Nogo receptor signaling and synaptic plasticity in health and disease (chaired by: L. Olson, Stockholm; C. Shatz, Stanford) |
| S24 | - | Cognition in a mini-brain: Systems neuroscience in drosophila (chaired by: G. Miesenböck, Oxford) |
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Monday, July 5, 2010 |
| 15:45 - 17:15 |
| S25 | - | The stressed brain: What makes us vulnerable? (chaired by: D.J.F.F. De Quervain, Zürich) |
| S26 | - | Cross-modal reorganization in deafness (chaired by: A. Kral, Hamburg) |
| S27 | - | Systems biology of the synapse: Concepts to understand the complexity of brain synaptic signaling (chaired by: E.D. Gundelfinger, Magdeburg) |
| S28 | - | Navigation and the head direction system: Insights from animals, humans and computational models (chaired by: T. Wolbers, Edinburgh) |
| S29 | - | State dependent cortical processing (chaired by: S. Crochet, Lyon; J. Poulet, Berlin-Buch) |
| S30 | - | Investigating glia function in vivo (chaired by: T. Fellin, Genova) |
| S31 | - | Act and select: The role of the striatum in selection of behaviour (chaired by: J.P. Bolam, Oxford) |
| S32 | - | Morphogens in neural circuit formation (chaired by: P. Bovolenta, Madrid) |
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Tuesday, July 6, 2010 |
| 09:45 - 11:15 |
| S33 | - | Fine-tuning the brain: MicroRNAs (chaired by: E. Vreugdenhil, Leiden; G. Schratt, Heidelberg) |
| S34 | - | Neurobiological factors determining high vulnerability to drug seeking and relapse (chaired by: T.J. De Vries, Amsterdam) |
| S35 | - | Rapid neuroendocrine response and synaptic plasticity (chaired by: S.L. Lightman, Bristol) |
| S36 | - | Prefrontal and parietal-premotor contributions to free choice selection (chaired by: B.M. De Jong, Groningen) |
| S37 | - | Sensorimotor integration in the whisker system (chaired by: P. Krieger, Stockholm; A. Groh, Munich) |
| S38 | - | Nitric oxide in sleep and sleep disorders (chaired by: T. Porkka-Heiskanen, Helsinki) |
| S39 | - | Cell-specific regulation of visual cortical plasticity (chaired by: T. Pizzorusso, Pisa; A. Maffei, Stony Brook) |
| S40 | - | Neuron-microglia interactions: A family matter from marriage to divorce (chaired by: M. Bentivoglio, Verona) |
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Tuesday, July 6, 2010 |
| 15:45 - 17:15 |
| S41 | - | In vitro study of human epileptogenic cells and networks (chaired by: F. Bartolomei, Marseille; P. Kahane, Grenoble) |
| S42 | - | The choroid plexus: A gate for signalling into the brain (chaired by: J.A. Palha, Braga; I. Torres Aleman, Madrid) |
| S43 | - | Molecular, cellular and network basis of thalamocortical dynamics (chaired by: N. Leresche, Paris) |
| S44 | - | Striatal plasticity: From health to Parkinson’s disease (chaired by: E.C. Hirsch, Paris; P. Calabresi, Perugia) |
| S45 | - | The relation of ongoing brain activity, stimulus evoked responses and perceptual decisions (chaired by: A. Kleinschmidt, Gif/Yvette ) |
| S46 | - | Stress and the amygdala: From animal models to clinical implications (chaired by: S. Chattarji, Bangalore) |
| S47 | - | Interneuron development and function (chaired by: S. Butt, London) |
| S48 | - | Presynaptic short-term plasticity: Molecules, mechanisms and functions (chaired by: ; N. Brose, Goettingen) |
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Wednesday, July 7, 2010
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| 09:45 - 11:15 |
| S49 | - | Dynamic processes underlying synaptic plasticity (chaired by: M. Kneussel, Hamburg; D. Choquet, Bordeaux) |
| S50 | - | Dopaminergic modulation of human decision making (chaired by: R. Cools, Nijmegen; M. Ullsperger, Cologne) |
| S51 | - | Recipe for solving the cerebellar mystery: 2 photons, 1 live mouse and a dash of Oregon Green BAPTA (chaired by: A. Konnerth, Munich; Y. Yarom, Jerusalem) |
| S52 | - | Neuronal cell death in motor neuron diseases (chaired by: A. Poletti, Milano; C. Miller, London) |
| S53 | - | How we come to experience that we own our body: from full-body illusions to cortical mapping (chaired by: H.H. Ehrsson, Stockholm) |
| S54 | - | Neuregulin signaling in neural development, function and disease (chaired by: A. Buonanno, Bethesda; J. Neddens, Bethesda) |
| S55 | - | Temporal control of neuronal diversity (chaired by: V. Tarabykin, Goettingen; P. Vanderhaeghen, Brussels) |
| S56 | - | Deletion of memory (chaired by: T. Hucho, Berlin) |
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TECHNICAL WORKSHOPS
Click on the number on the left to have the full description of the technical workshop.
| Saturday, July 3, 2010 |
| 12:30 - 15:30 |
| W01 | - | Imaging dynamic changes at the synapse (chaired by: J. Henley, Bristol) |
| W02 | - | Strategies for promoting peripheral nerve regeneration (chaired by: S. Geuna, Orbassano, Torino; M.M. Sousa, Porto) |
| W03 | - | Novel methods for assessing transmitter release and effects during behaviour (chaired by: M.G.P. Feenstra, Amsterdam) |
| W04 | - | Neuroanatomical tracing and systems neuroscience: the state of the art (chaired by: J. Lanciego, Pamplona; F.G. Wouterlood, Amsterdam) |
| W05 | - | From neurons to networks – new approaches in electrophysiology (chaired by: R. Polder, Tamm; A. Draguhn, Heidelberg) |
| W06 | - | Structure, dynamics and function in large scale neuronal ensembles (chaired by: S. Marom, Haifa) |
| W07 | - | Optogenetic manipulations of synaptic transmission, plasticity, vision and behaviors (chaired by: A. Gottschalk, Frankfurt; T.G. Oertner, Basel) |
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POSTER SESSIONS
Poster sessions will be held in the Europa hall of the RAI Conference Center, the main hall also for the registration, exhibition, internet and catering areas. There will be 7 poster sessions, each scheduled for half a day.
As a poster presenter you may have the chance to be selected for the Amsterdam Young Scientist Award of € 5,000 if you are below the age of 35. Further information will be available on this webpage once the poster programme is published. See also Students page.
Morning poster sessions are scheduled between 09:45 and 13:15; afternoon poster sessions are scheduled between 13:30 and 17:30. A one hour time block is reserved for the presence of the authors of odd- and even-numbered posters respectively (11:15-12:15 & 12:15-13:15, in the morning; 13:30-14:30 & 14:30-15:30 in the afternoon).
Poster boards will be sized 1.50 m wide, 1.00 m high.
Abstract submission will be open as from December 1, 2009 and will close on February 1, 2010 (included).
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Last update: January 28, 2010
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